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Erectile dysfunction
Treatment of erectile dysfunction has been changed beyond all recognition in the last few decades. Safe and reliable treatment is now at hand for most men who need it.
Cialis is a treatment for erectile dysfunction. It works in a similar way to Viagra (sildenafil), Levitra, and Spedra, and has similar side effects.
The proper medical name for Cialis is tadalafil. Tadalafil, like the other commonly used erectile dysfunction tablets, is a PDE5 inhibitor, which means it works by inhibiting an enzyme called phosphodiesterase. This in turn changes the blood flow in the penis and improves erections.
A single Cialis tablet will usually remain active for 36 hours, which is longer than Viagra/sildenafil, Levitra, or Spedra. Cialis is sometimes called the ‘weekend pill’ because it works for longer than other treatments. Like other erectile dysfunction tablets, Cialis only works if there is sexual stimulation. If there is no stimulation, Cialis remains inactive. After 36 hours the effects wear-off.
With all of the publicity surrounding ‘the little blue pill’, it may seem as though you could just borrow one from a friend to help you regain your sex life. But while Viagra is effective, and has relatively few side effects, it is a prescription-only medicine and must be taken under a doctor’s care.
UPDATE APRIL 2018: Viagra Connect contains sildenafil 50mg and is now available over the counter from a pharmacist.
Some patients are not good candidates for Viagra; due to certain medical conditions or other medications they are taking they may be at higher risk of side effects. Erectile dysfunction can be indicative of an underlying health condition that should be treated before considering Viagra, and still other cases of ED are psychological, requiring counselling and therapy instead of medication.
Learn why it is important that Viagra, and all other PDE5 inhibitors, be taken only under a doctor’s care.Read in full
One of the most common questions associated with sildenafil (Viagra) and other PDE5 inhibitors is how long does it last?
The simple answer is usually around 4 hours, with the maximum effect between 30 mins and 2.5 hours after taking – see graph below. However several factors will have an effect on how quickly the drug is absorbed and expelled from the bloodstream.
The following timeline has been collated from several studies:
First responders: 12 minutes Some men report achieving an erection as quickly as 12 minutes.
Average responders: 27 minutes Most men start to feel the benefit of sildenafil after 27 minutes.
Maximum effect: 57 minutes After 1 hour, the maximum concentration of the drug is in the bloodstream (this may increase by another hour if food was eaten prior to taking sildenafil).
Half mast: 4 hours Sildenafil has a 4-hour ‘half-life’, meaning half of the drug has left the bloodstream after 4 hours.
Still effective?: 10 hours Some men may still be able to achieve a satisfactory erection after 10 hours, although the duration will become shorter.
All gone: 24 hours After 24 hours all traces of the drug in the bloodstream has practically gone.
As soon as a potential patient thinks of taking medicine for erectile dysfunction, these practical questions come into play:
who can take it?
what is the drug composed of?
when should you take it?
how long does it last?
Though specific questions or concerns should always be discussed with a doctor, it never hurts to be informed about any medicine you are thinking of taking. Read in full
Erectile dysfunction is widely recognised as a quality-of-life issue that affects self-confidence and relationships, but experts agree that erections, or erection problems, can also be a measure of mens’ general wellbeing.
Some go so far as to claim that the penis is the barometer of a man’s health. And though it can be argued that due to the large number of possible causes of erectile dysfunction (ranging from psychological issues to the side effects of medication), a man’s ability to achieve an erection is not always indicative of his overall state of health, a number of studies prove that in otherwise healthy men erectile dysfunction can be an early sign of heart disease. Read in full
If you have erectile dysfunction, desperation can drive you to consider almost any option. But it’s important to avoid the temptation of buying any drug that isn’t currently licenced and regulated for sale in the UK, particularly when buying online. Read in full
Update February 2023: Branded Levitra has been discontinued by the manufacturer (Bayer).
Drug manufacturer Bayer’s patent on Levitra expired 31 October 2018, following in the footsteps of Pfizer’s Viagra and Lilly’s Cialis, whose patents expired in 2013 and 2017 respectively.
A phosphodiesterase-5 (PDE5) inhibitor, Levitra was introduced to the market in 2003, around the same time as Viagra and Cialis. It enhances blood flow to the penis during sexual stimulation by inhibiting the PDE5 enzyme normally responsible for regulating, or limiting, that blood flow.
Also known by the name of its active ingredient, vardenafil, Levitra offers help with sexual performance and improves sexual relationships affected by erectile dysfunction. Read in full
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The so-called ‘weekend pill’ will soon be made by generic manufacturers, as Eli Lilly’s patent on the drug is expected to expire in the UK 14 November 2017, and will be made available soon after from Dr Fox.
The patent for Cialis expired in March 2015 in Brazil, and is now available in that country as generic tadalafil from Sandoz.
Cialis comes onto the scene
Containing the active ingredient tadalafil, Cialis was introduced to the market in 2003, to compete with Pfizer’s erectile dysfunction medicine Viagra. It was originally developed to relieve frequent urination or weak flow of urine in patients with enlarged prostates, but it also helps increase blood flow to the penis. Read in full
Club drugs include Ecstasy (MDMA), the ‘date rape drug’ (Rohypnol), Crystal meth or Speed (Methamphetamine), acid (LSD), Special K (Ketamine) and Poppers (amyl nitrates). Increasingly the dangers of these drugs are escalated by taking more than one at the same time.
Typically taken at raves, parties, and clubs, these drugs are used to enhance or distort sensations and perceptions, to feel euphoric, and experience greater enjoyment. They are perceived to increase self-confidence and physical energy.
Of course these drugs are illegal for a reason. They have adverse effects and can be dangerous, even fatal. Problems arise from toxicity due to excessive dose, from interactions, and due to impurities. Illegal drugs are not monitored for quality. Read in full