Doxycycline | Malarone (generic & branded) | Lariam (mefloquine) | |||
---|---|---|---|---|---|
Brand name | |||||
Many different | Malarone (GSK) or non-branded | Lariam | |||
Dosage | |||||
100mg capsule. One capsule daily with food | Combined tablet 250mg atovaquone/100mg proguanil. One tablet daily with food | 250mg tablet. One tablet weekly on the same day each week | |||
When to start before entering malaria zone | |||||
2 days before | 2 days before | 10 days before | |||
When to stop after leaving malaria zone | |||||
4 weeks after | 7 days after | 4 weeks after | |||
Number of tablets/capsules for 1 week trip | |||||
37 capsules | 16 tablets | 8 tablets | |||
Side effects and cautions | |||||
Intestinal upset, vaginal thrush, heart burn. Increased skin sensitivity to bright sun. | Intestinal upsets, headache. | Intestinal upset, headache, loss of balance, dizziness. Less common: sleep and mental disturbance. Caution driving or operating machinery. | |||
Duration of long term use | |||||
2 years | 1 year | 3 years | |||
Manufacturer's Patient Information Leaflet (PDF) | |||||
Leaflet | Leaflet | Leaflet |